TriLink BioTechnologies Nucleotides
It is likely that among TriLink’s wide selection of modified nucleoside triphosphates (NTPs) you will find a compound to suit your application. We stock over 150 modified compounds, including Aminoallyl, Biotin and 2' Fluoro nucleotides. In addition, we offer specialty modified nucleotides such as bisphosphates, a series of monophosphates and CAP and mCAP. Whether your studies involve indirect DNA labeling, cDNA synthesis, nuclease resistance or a new application, we have the right modified NTP. Additionally, our nucleic acid chemists are experts in the synthesis of unique NTPs. Please inquire for larger quantities or specific concentrations.
TriLink BioTechnologies Custom Chemistry
Our custom chemistry and contract research services include synthesis of unique phosphoramidites and polyphosphates, including mono-, di- and triphosphates, and other small molecules. If the small molecule your research requires is not commercially available, contact us. Collectively, our R&D team has decades of experience developing and optimizing nucleic acid synthesis schemes.
A New Approach to Early Phase Therapeutic GMP Manufacturing
For over 20 years, we’ve been industry leaders synthesizing high quality research and diagnostic grade material, especially difficult and unusual constructs. Now we’re combining our expertise with a new state-of-the art GMP manufacturing facility to expand our services into mRNA and oligonucleotide therapeutics.
Our new, 2,000 square foot GMP facility is dedicated to manufacturing therapeutic products and is ISO certified by Lloyd’s Register. The controlled labs feature:
Manufacturing of therapeutic grade material is available for:
To begin discussions and obtain a quote for your project, please send us a request. We’ll start with an intake meeting, where we’ll discuss your project, expectations and timelines. From there, we’ll work with you to determine the most effective and efficient process for your particular project. Although we may customize each project to meet your specific needs, the basic steps are outlined below.
mRNA and Long RNA
For over 18 years TriLink has been an industry leader in manufacturing high quality RNA. We are pleased to now offer the best mRNA and long RNA. These new product lines feature custom synthesis of mRNA and long RNA (up to multiple kilobases) with a wide array of modification services at scales ranging from micrograms to grams. We also offer stocked mRNA products including reporter gene and expression factor mRNA. All of our mRNA and long RNA products offer:
Affordable Custom Synthesis
Genome Editing & Manipulation Tools
Zinc-finger nucleases, TALENS, CRISPR and recombinases
Gene Replacement, Immunotherapy & Delivery Optimization
mRNA for non-integrating generation of iPSCs
Please contact us to discuss your path to pharmaceutical GMP manufacturing.